Mina Sumita
Associate Professor, Biochemistry
Department of Chemistry
Southern Illinois University Edwardsville
College of Arts and Sciences
SW 3230 (Office) / SW 2005 (Laboratory)
Edwardsville, Illinois 62026-1652.
Tel: (618) 650-2420 (Office)
Fax: (618) 650-3556
E-mail: [email protected]
Education:
- Ph.D., Wayne State University (2006)
- M.S., University of Colorado at Denver (1999)
- B.A., University of Colorado at Boulder (1995)
Research Interest:
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My core research interests are incorporation of natural and unnatural modified nucleotides for biochemical and biophysical studies and analysis of the structural and functional effects of RNA modification. The specific aims are 1) understanding structural and functional effects of modified nucleotides on snRNAs by biophysical studies including NMR spectroscopy, 2) designing and synthesizing unnatural modified nucleotides to study RNA biochemistry and biophysical chemistry, and 3) developing DNA/RNA aptamers with modified bases.
Teaching Interest:
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Biochemistry and Biophysical Chemistry courses
Selected Publications:
- Das, P.K., Adil, O., DeGregorio, A.P., Sumita, M., and Shamsi, M.H. Pseudouridine-modified RNA probe for label-free electrochemical detection of Nucleic Acids on 2D MoS2 Nanosheets Analyst, 2024, 149, 1310-1317 DOI: 10.1039/d3an01832f
- Sanford, T., Riley, A., Clawson, M., Raasch, K., Oyebamiji, R., Sumita, M. Incorporation of Pseudouridine into RNA for Biochemical and Biophysical Studies, RNA Structure and Function, (Barciszewski, J., Rajewsky, N., eds.). 2023, 575-594, Springer-Nature, Berlin. DOI: 10.1007/978-3-031-36390-0_25
- Riley, A.T., Sanford, T.C., Woodard, A.M., Clerc, E.P., Sumita, M., Semi-Enzymatic Synthesis of Pseudouridine, Bioorganic & Medicinal Chemistry Letters, 2021, 44, 128105. DOI: 10.1016/j.bmcl.2021.128105
- Mazrouei, R., Huffman, B., Sumita, M., Shavezipur, M.. Development of an impedance-based interdigitated biochemical sensor using a multiuser silicon process, Journal of Micromechanics and Microengineering. 2019, 29. DOI: 10.1088/1361-6439/ab078f
Patents:
- Shavezipur, M., Sumita, M., Mazrouei, R. “Pathogen Transport Modelled Biomimetic Sensor, Sensing Method, and Produce Sanitization”, US Patent 11480458, Oct. 25, 2022
